MORPHOMETRIC STUDY OF PLACENTA IN MEDICAL DISORDERS OF PREGNANCY

Bhakti Kalyankar*, Vijay Kalyankar, Shailesh Vaidya and Abhilash Zambare

ABSTRACT

Introduction— We studied the various pathological changes in placentae in medical disorders of pregnancy and compared with those of normal placentae and its fetal outcome. Objectives- To correlate the pathological changes of Placentae with the fetal outcome and mode of delivery. Material and Methods— 400 placentae were studied in 2 years period from women who delivered at labour room of our rural Govt. medical college hospital, Ambajogai, Maharashtra, India. Of these, 200 were from normal term pregnancy (control group) and 200 from women having medical disorder during or associated with pregnancy that were randomly selected (study group). The gross and microscopic features of both groups were studied and their findings correlated with the mode of delivery and fetal outcome. The feto-placental ratio and placental coefficient were evaluated. Results- The majority of Placentae from medical disorders in pregnancy show pathological changes directly in proportion to severity of medical disorder and correlate positively for increase in fetal jeopardy, fetal distress, Perinatal deaths and low Apgar scores, and increase in Caesarean deliveries. Conclusions— Gross and microscopic examination of Placentae should be performed in all cases of medical disorders in pregnancy where pregnancy outcome is abnormal.

Keywords: Medical disorders of pregnancy, placentae, pathological changes.