EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

RISK OF INFECTIVE ENDOCARDITIS IN TAIWAN: RETROSPECTIVE COHORT STUDY

Yueh-Chin Chung, PhD*

ABSTRACT

Background: The incidence rate of infective endocarditis (IE) in Taiwan is high. Thus, we investigated the incidence and risk factors of IE among Taiwanese patients. Objective: In this retrospective cohort study, IE cases from 1998 to 2010 were identified from the National Health Insurance Research Database through the International Classification of Diseases, Ninth Revision, Clinical Modification. Poisson regression models were used to assess the relative risks (RRs) and 95% confidence intervals (CIs) of IE associated with sex, age, and odds ratios (ORs) of comorbidities. Among 16,924 patients with IE, 108,22 (51.60%) were male and 6,102 (48.40%) were female. Results: A total of 59.29% patients were older than 50 years. The annual crude incidence was 4.34–6.86 per 100,000 person-years. Our data also demonstrated that the highest incidence rate was on people aged 70–79 years. The incidence rate of IE was higher in males than in females in the 40- to 49-year-old group (RR = 3.12; 95% CI, 2.84–3.43). Staphylococcal (61.38%) and Streptococcal species (28.44%) were the most common causative pathogens. Males showed more statistically significant comorbidities of hypertension (OR = 5.58; 95% CI, 4.32–7.20), disease of aortic valve (OR = 5.01; 95% CI, 4.13–6.08), acute respiratory failure (OR = 9.23; 95% CI ,7.23–11.78), and drug abuse (OR = 6.39; 95% CI, 3.37–12.13) (p < 0.0001) than females. Conclusions: The Taiwanese study revealed a high incidence of IE in men and elderly subjects. Staphylococcal species and cardiovascular and infective valve prevention strategies may help reduce the risk of IE.

Keywords: infective endocarditis, incidence, relative risks, age distribution, prospective cohort study.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )