SCHIFF BASE: MULTIDISCIPLINARY TOOL IN CHEMISTRY
R. G. Mahale* and Deepak V. Nagarale
ABSTRACT
Schiff bases are the compounds which are mainly formed by the condensation of the aldehydes and amines. In this review, an attempt is made to present a current scenario of these compounds which is synthesized by various synthetic methods. Some of those are easily synthesized from the various heterocyclic rings like furan, pyridine, thiophene and most important triazoles especially 1,2,4- triazole. These can also be convert in to metal complexes and reactants that are involved in the formation of this category of Schiff base compounds are called as “chelating agents”. Some other compounds which were review here like Chalcones and their heterocyclic analogues, belong to the flavanoid family, which acquire a number of attractive biological properties like antioxidant, cytotoxic, anticancer, antimicrobial, antiprotozoal, antiulcer, antihistaminic and anti-inflammatory.
Keywords: antioxidant, cytotoxic, anticancer, antimicrobial, antiprotozoal, antiulcer, antihistaminic.
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