CHROMATIN DETECTION METHODS-DIAGNOSTIC SCOPE IN ORAL PATHOLOGY
Dr. Supraja S.*, Dr. Bhavana S. B., Dr. A. Anuradha, Dr. G. Vijay Srinivas, Dr. Puneeth H. K., Dr. Kiresur Md. Asif
Study of chromatin from the earliest stages of embryonic development to senescence are important for understanding the basis of normal gene expression in health and the causes of gene dysregulation in human diseases. With the availability of newer technologies and a highly sophisticated environment, this review provides unique opportunities to know the various methods to study chromatin architecture such as Cellular strains, Micropipette aspiration, Atomic force microscopy, Particle-tracking microrheology, Fractal dimension of chromatin, Chromatin Immunoprecipitation and MiniChIP-chip.
Keywords: Chromatin, Atomic Force Microscopy, Fractal Dimension, Immunoprecipitataion.
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