EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

STUDY ON DRUG RELATED PROBLEMS IN TUBERCULOSIS PATIENTS WITH COMORBIDITIES IN A TERTIARY CARE TEACHING HOSPITAL

Dr. G. Shivaraj*, Dr. K. Muralikrishna, Nijeesh C. H., Laloo F., Baburaja B. and Dr. H. Doddayya

ABSTRACT

The presence of comorbidities in tuberculosis patients like hepatic disorders, renal failure, diabetes mellitus and hypertension etc. require more attention to improve the effectiveness of drug therapy and reducing drug related complications like hepatic toxicity, hyperuricemia, renal failure etc. To understand the drug related problems in tuberculosis patient with comorbidities, a prospective observation based study on drug related problems in tuberculosis patient with comorbidities was conducted in 1000 bedded tertiary care teaching hospital over a period of six months from November 2015 to April 2016. The data was collected from 100 in-patients using specially designed data collection form. Out of 100 patients, 45 cases with hepatic impairment, 30 cases with diabetes, 17 cases with lower respiratory tract infection, 5 cases with hypertension and 3 cases with chronic obstructive pulmonary disease were found. In this study, total 585 drugs related problems have been identified in 100 patients by using 8 categories of Pharmaceutical Care Network Europe drug related problems classification. Drug interactions (50.26%) was the most common drug related problems found, which was clinically significant in tuberculosis patients with comorbidities. Drug choice problem (40.68%) was the second most common drug related problems found, which consists of inappropriate use of drugs (74.37%) like antibiotics and acid suppressant drugs. Hepatic impairment was common for most of the tuberculosis patients with anti-tubercular drugs but in future we have to give more attention on management of tuberculosis in diabetes, hypertension and other comorbidities and associated drugs related problems.

Keywords: Tuberculosis, Comorbidities, Drug Related Problems, Drug Interactions, Drug Choice Problems.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )