EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

DRUG UTILIZATION PATTERN AND EFFICACY ANALYSIS OF DRUGS USED IN DIABETIC PERIPHERAL NEUROPATHY BY NERVE CONDUCTION STUDY IN A TERTIARY CARE HOSPITAL

Rajesh M.*, Mohapatra S., Swain TR., Mallik AK.

ABSTRACT

Objective: Diabetic peripheral neuropathy (DPN) is the most common and distressing late complication of diabetes mellitus affecting nearly 50% of diabetic patients and treatment failure cases may develop foot ulcers and gangrene requiring amputation. DPN is responsible for 50% to 75% of non-traumatic amputations. Hence this study is aimed to assess the Drug utilization pattern in patients with DPN in a tertiary care hospital and compare the efficacy of drug used. Method: Data was collected in a preformed proforma and efficacy of the drugs used was assessed by Nerve Conduction Study (NCS) at 0 week and 12th week. Results were analysed statistically. Result: Pregabalin was prescribed to 66% patients, Gabapentin to 42% and Amitriptyline to 12%. In NCS, significant improvement was observed by Pregabalin at 12th week in both axonal and demyelinating type of neuropathy, unlike gabapentin and Amitriptyline. Conclusion: Pregabalin was the most frequently prescribed and more effective drug than gabapentin and Amitriptyline.

Keywords: Diabetic Peripheral Neuropathy, Nerve conduction study, Efficacy.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia