EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

STUDY OF THE ANTIOXIDANT POTENTIAL OF SOLVENT EXTRACTS OF RHIZOMES OF BERGENIA STRACHEYI

Reena Purohit, Sandeep Kumar* and Abhishek Mathur

ABSTRACT

Medicinal plants are gaining global attention owing to the fact that the herbal drugs are cost effective, easily available and with negligible side effects. The beneficial effects of the medicinal plants in health care can be well judged from the WHO estimate that around 80% of the world population uses them in some form or the other. It is important to note that homeopathy and modern medicine have their roots in medicinal plants. The compounds derived from medicinal plants form the ingredients of analgesics, antibiotics, heart drugs, laxatives, anti-cancer agents, ulcer treatments, contraceptives, diuretics etc. Compounds from plants are referred as plant secondary metabolites, phytochemicals, anti-nutritional factors, plant xenobiotics etc. In the present investigation, in vitro antioxidant activity of solvent extracts of Bergenia stracheyi was determined by total phenolic content, DPPH radical scavenging method, superoxide anion radical scavenging assay and total antioxidant activity. The results confirmed that, polar extracts possessed higher antioxidant activity followed by non polar extracts. It was found that, TPC in ethyl acetate, aqueous and methanol were found to be 246, 235 and 232μg/g gallic acid equivalents followed by petroleum ether and hexane extracts viz. 187 and 134μg/ml. IC50 values of ethyl acetate, aqueous and methanol extracts were found to be 22.5, 25.56 and 35.23μg/ml followed by 52.57 and 85.56μg/ml of petroleum ether and hexane extracts respectively. With reference to superoxide anion radical scavenging method polar extracts showed 78-82% inhibition of superoxide followed by non polar extracts having 54-63% inhibition. Total antioxidant activity also followed the same order. Ascorbic acid was used as the standard antioxidant having IC50 value 55.45μg/ml in DPPH radical scavenging method and 87.80% inhibition of superoxide. Different conventional methods were followed to determine qualitatively the presence of phytochemical constituents present in the solvent extracts. The ethyl acetate extracts possessed tannin, steroids, saponin and glycosides, alkaloids and flavanoids while aqueous and methanol extracts showed the absence of saponin and glycosides. Petroleum ether extracts possessed only steroids and saponin while hexane extracts showed the presence of saponin only.

Keywords: Antioxidant activity, solvent extracts, Bergenia stracheyi, phytochemical screening.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 December 2021 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • EJPMR: DECEMBER ISSUE PUBLISHED

    DECEMBER Issue has been successfully launched on 1 December 2021.

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )