EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

A STUDY OF INFLAMMATORY MARKERS (CRP, ADA & ESR) IN HYPOTHYROIDISM

Shyam Sundar Yadav*, G. P. Singh and Sushil Yadav

ABSTRACT

Background: Hypothyroidism slows down the metabolic activities producing various causes weight gain, poor appetite, shortness of breath constipation etc. These are associated with the immune deregulation which ultimately produces the inflammation. Inflammatory markers can be helpful assessment in diagnosis of hypothyroidism is not very well studied in the past. So, the goal of the study is to investigate role of these inflammatory (CRP, ADA &ESR) in hypothyroidism. Material and Methods: The study consists of 30 patients diagnosed with hypothyroidism and 30 healthy controls. The serum Total TSH, T3 &T4 were estimated by enzyme immunoassay competition method with ELFA technique by using automated VIDAS for the conformation of hypothyroidism. The concentration of CRP and ADA activity were determined on semi auto analyzer by quantitative turbidimetric methods. Similarly, ESR level were estimated by westergren tube method. Results: In the study, the mean CRP value (10.66±7.81) mg/dl, ADA (24.47±6.47) U/L & ESR (16.57±5.68) mm/hr were found significantly higher in hypothyroid patients in comparison to healthy controls. Similarly, there was no correlation obtained between TSH, T3 &T4 and CRP, ADA & ESR. Conclusion: The study has shown that there is significant increase in mean CRP, ADA &ESR level in hypothyroid patients in comparison to healthy controls.

Keywords: ADA, CRP, ESR, Hypothyroidism.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )