EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

PHYTOCHEMICAL, ANTIOXIDANT AND ANTIMICROBIAL STUDY ON RIND OF THE FRUIT EXTRACT OF Punica granatum Linn.

V. E. Ida Christi*, S. Mohan, S. Swarna Kumari, T. K. Sreehari, R. Karthiyaraj, N. K. Franklin

ABSTRACT

Punica is a small genus of fruit bearing deciduous small tree. According to legend, pomegranates grew in the Garden of Eden, and the fruit has been used as a folk medicine for thousands of years.[1] Pomegranate fruit peel is a rich source of polyphenoles, and also contain potentially pharmacologically active chemicals including the sapogenin steroid, Chlorogenin, flavonoids etc.[2] Peel contain phenolic punicalagins, gallic acid and other fatty acids, catechine and some flavonoids, flavons and anthocyanins.[3] This present study reveals an account of updated information about some of the physicochemical characters, phytochemical nature, antimicrobial activity and antioxidant activity of aqueous and alcoholic extract of the fruit rind. Here the physicochemical parameters like ash values, extractive values and total fiber contents were estimated. The total phenol and flavonoids content, inorganic minerals like sodium and potassium were estimated. The flavonoid present in the rind was isolated and its Rf values were calculated by HPTLC method, and it was compared with that of the standard epicatechine. The antioxidant activity of the alcoholic extract was evaluated by Reducing power ability, DPPH method and Hydrogen peroxide methods. Aqueous and alcoholic extracts were screened for their antibacterial and anti fungal activities and compared with that of the standards like Amikacin and Ketakonazole. The alcoholic extract shows significant antioxidant activity and both extracts shows good antimicrobial activity, but the aqueous extract is more active towards all bacteria and fungi organisms. This plant drug consist of polyphenols and flavonoids, it may have the antimicrobial and antioxidant activity, it has been used for many applications in food preservations, pharmaceuticals, Neutraceuticals and natural therapies.

Keywords: epicatechine, pharmacognosy, Neutraceuticals, Amikacin, Ketakonazole.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia