A PROSPECTIVE STUDY ON MEDICATION ADHERENCE AMONG PATIENTS WITH TYPE 2 DIABETES MELLITUS IN SOUTH INDIAN TERTIARY CARE HOSPITAL
Roshin Elizabeth Mathew, Aswathy Vijayan, Mamen Alex, Veena Vijayan G.* and Dr. Archana Babu
Aim: The main objective of the study was to evaluate Medication Adherence and also to find its association with Severity of Depression in Type 2 Diabetes Mellitus patients. Materials and Methods: A prospective-observational study carried out among 200 patients with Type II Diabetes Mellitus in the General Medicine Department for a period of six months based on inclusion and exclusion criteria. A structured interview with patient or parent was conducted by using various questionnaires to elicit information about severity of depression by Hamilton Depression Rating scale(HAM-D) and medication adherence using Morisky Medication Adherence Scale-8(MMAS-8). Then data were well analyzed. Finally, correlation between Medication Adherence and Severity of Depression were assessed. Result: Majority of them shows (57%) high adherence, followed by medium adherence only 14.5% show low adherence. About 27.6% of poor adherence to anti-diabetic medication is due to forgetfulness, lack of disease knowledge, Long treatment duration, Increased cost of therapy, lack of family or social support, Polypharmacy, only 6.5% due to side effects of medicine especially for patients on insulin. Diabetics without depression are highly adherent to medication (49.1%) medium adherence (28.1%), only 13.8% shows low adherence. Majority of diabetic patients with severe/very severe depression shows low adherence to medication (44.8%), followed by medium adherence (28.1%) and only 9.6% are highly adherent. Conclusion: The studies on medication adherence will definitely help the physician to improve the prescribing pattern, efficient clinical management delays the progression of disease, reduce the diabetic related complications, improves the quality of life, improves clinical outcomes of patients and better QOL of patients.
Keywords: Diabetes Mellitus, Depression, Medication Adherence, MMAS-8, HAM-D.
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