( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57



*Fozia Jamal, G.P. Singh and Sushil Yadav


Background: Prolactin is a peptide hormone secreted by the adenohypophysis. The secretion of prolactin is controlled by the hypothalamus. There are some others factors such as vasoactive inhibitory peptide (VIP) and thyrotropin releasing hormone (TRH) which enhance the prolactin secretion. Hyperprolactinemia is a clinical condition characterized by the hyper secretion of prolactin in both male and female that can result from a number of causes including hypothyroidism. The aim of this study were to estimate the serum prolactin level in patients with hypothyroidism and to find out the correlation between serum thyroid stimulating hormone (TSH) and prolactin level. Material and methods: A total number of 60 samples were taken; among these 30 were hypothyroid patients and 30 controls. The study group and control group were well matched in regard to age and sex. Fasting venous blood samples has been taken from each individual and analyzed for TSH, T3, T4 and prolactin by ELFA (enzyme linked fluorescent assay) technique using VIDAS analyzer. Obtained data was analyzed by using SPSS. Results: Differences between mean serum prolactin levels among hypothyroid patients and controls were statistically significant (p= 0.005). No correlation was found between serum prolactin and TSH levels (r= -0.194, p= 0.303). Conclusion: Serum prolactin level was found to be increased in hypothyroid patients as compared to that of controls. If thyroid function tests are normal in patients with raised prolactin level, further test should be done to find out the etiology of hyperprolactinemia.

Keywords: Hyperprolactinemia, Hypothyroidism, Prolactin.

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia