PHARMACEUTICAL AND BIOLOGICAL EVALUATION OF A POLYHERBAL TOOTHPASTE
Bhagyasri Y.*, Ramaiah Maddi, Siva Subramanian N., Pavan Kumar Sara and Suman Vadithya
The demand for herbal based product such as toothpaste is high in these days. Consumers believed by using herbal based toothpaste are safe, effective and less toxicity because less and only safe chemical used as compared to the synthetically produced toothpaste. Therefore, this study was aimed to formulate and evaluate new polyherbal toothpaste for antibacterial activity. In the present study, we are prepared two different formulations for making toothpaste. In formulation-1, three ingredients (Neem leaf, Amla seeds and Tulsi leaves) and in formulation-2 (Clove bud and Neem bark) compared with standard Meswak toothpaste. The formulations were subjected to various pharmaceutical evaluation tests like homogeneity, pH, spreadability, abrasiveness, foaming ability, tube inertness, and stability studies. All the results are within the range of pharmaceutical grade and the formulation is comparatively equal and rarely better than marketed formulation. Hence the selected formulation of toothpaste was found to be ideal for large scale manufacturing.
Keywords: Meswak Herbal Toothpaste, Pharmaceutical Evaluation, Antibacterial Activity.
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