EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EFFECTIVENESS OF SOFOSBUVIR DRUG IN THE TREATMENT OF HEPATITIS C INFECTION IN POST RENAL TRANSPLANT PATIENT

Dr. Abel Abraham Thomas* and Ms. Alfiya Ali

ABSTRACT

Hepatitis C is an infection caused by the Hepatitis C virus that attacks the liver and leads to inflammation. Being a communicable disease Hepatitis C has now become of the major reason for morbidity and mortality. The evidence suggests that chronic hepatitis c plays a detrimental role in survival among patients on maintenance dialysis or renal transplant recipient promotes the antiviral treatment of hepatitis c virus (HCV) among chronic kidney disease patients. Interferon based regimens have provided limited efficacy and safety among chronic kidney disease patients, whereas the advent of new direct acting antiviral for the treatment of hepaitisc (launched over the past 5 years) have given the opportunity to reach sustained virologic response rate of 90% for many patient groups. Sofusbovir has high efficacy in treating HCV in patients who were counteracted to the drug interferon. The viral load of the patients shows almost undetectable after 4weeks of treatment. It is also efficient in treating all genotype. Thus, the antiviral regimens based on direct acting antivirals promise to play a pivotal role in the eradication of hepatitis c among kidney disease patients. Direct acting antiviral are very expensive; in an era of cost containment this is a crucial point either in developed and developing countries.

Keywords: Hepatitis C, Anti Viral, Ribavirin, Interferon, Viral Load, Direct-Acting Antiviral, Sobosfovir.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )