EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

ASSOCIATION OF GAMMA GLUTAMYL TRANSFERASE AND BLOOD LIPID LEVELS IN TYPE 2 DIABETIC SUBJECTS

Poonam Bai*, Fnu Sandeep, Sateesh Kumar, Sheena Shiwlani, Roopa Kumari and Jitesh Kumar

ABSTRACT

Objective: The present study analyzed the correlation of ϒ-glutamyl transferase (GGT) with the high density lipoprotein and low density lipoprotein in type 2 diabetics. Study Design: Case control study. Study setting & Duration: Department of Medicine- LUMHS Jamshoro, from January 2016 to September 2016. Subjects & Methods: 100 type 2 diabetics and 100 controls were selected through non-probability (purposive) sampling. Clinical history, physical examination and blood biochemical findings were noted in proforma. Biochemical tests were performed as per standard criteria on Roche Hitachi Chemistry Analyzer. GGT was detected by IFCC method. Data was analyzed at 95% confidence interval on the statistical package SPSS 22.0 (IBM, Incorporation, USA) and Microsoft excel. Results: The GGT was noted as 20.44±5.71 and 39.5± 5.56 U/L (P=0.0001) and the HDLc as 49.15±3.67 and 30.19± 10.61 U/L in controls and cases respectively (P=0.0001). GGT showed positive correlation with systolic BP, diastolic BP, blood glucose, HbA1c, creatinine, cholesterol, triglycerides and LDLc. Negative correlation was found of GGT with the HDLc (r= - 0.676, P=0.0001). Conclusion: The present study found negative correlation of GGT with HDLc but positive correlation with LDLc. Hence, the GGT may be exploited as a simple and inexpensive atherogenic biomarker instead of expensive lipid profile.

Keywords: Gamma-Glutamyl Transferase, HDLc, LDLc, Diabetes Mellitus.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia