( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57



Hussein Haleem Jasim


Background: Human saliva performs an important role in preserving healthy teeth and oral tissues. Many factors
have effects on saliva compositions and may interfere with function of saliva. X-radiation consider one of the most
important factors which have important effects on the saliva. Understanding the consequences of radiation still
valuable to many interested investigators. Aim of study: Monitor irradiation influence in radio-treated individuals
who had head and neck malignancies on the most organic and inorganic constitutes of human saliva. Material and
Methods: The study undertaken on individuals (80 male( aged between 30-45 years who referred to Radiation and
Nuclear Medicine Hospital in Baghdad for the period between Dec. 2013 to Oct. 2016, Forty of them are patients
with malignancies in head and neck after 12 weeks radiotherapy. The other forty were healthy individuals. A whole
dosage was between 40 - 44 Gray (5 fractions weekly with specific dosage of 2.0 daily). Assessment of most
salivary organic and inorganic components were carried out for all individuals after radiotherapy. The levels of
salivary total protein, albumin, immunoglobulin A, M and G, amylase, calcium,, phosphate, magnesium in all
subjects were measured utilizing specific tests. Results: The study showed a significant difference in the most
salivary organic constitutes between radio-treated patients group and healthy group, so the study showed a
significant increase of the levels of salivary total protein and albumin in patients with radiotherapy in compared to
healthy individuals. A significant reduction in the levels of salivary IgA and IgM in patients with radiotherapy with
a non-significant increase in the levels of salivary IgG in compared to healthy individuals. The study also showed a
significant decrease in the levels of salivary amylase in patients with radiotherapy in compared to healthy
individuals. Also, there was no significant difference of most inorganic constitutes in saliva between radio-treated
patients group and healthy group, so the levels of salivary Ca, P and Mg in radio-treated individuals in opposite to
healthy individuals. Conclusion: Long term exposure of head and neck region to x-radiation have adverse
influence on most component of saliva.

Keywords: X-radiation, Radiotherapy, Saliva, Salivary composition.

[Full Text Article] [Download Certificate]


  All Since 2019
 Citation  3086  2560
 h-index  18  17
 i10-index  64  44



  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 May 2024 Issue has been Published, Kindly check it on


    MAY 2024 issue has been successfully launched on MAY 2024.

  • EJPMR New Impact Factor

    EJPMR Impact Factor has been Increased to 7.065 for Year 2024.

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.


  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia