INFLUENCE OF COUPLE BODY MASS INDICES ON THE TREATMENT OUTCOMES AND EXPECTED NEONATAL BODY WEIGHTS ASSOCIATED WITH INTRACYTOPLASMIC SPERM INJECTION CYCLES

Tamer Fares*

ABSTRACT

Aim of Study: To investigate the effects of Egyptian couples’ body mass indices (BMIs) on the outcomes of intracytoplasmic sperm injection (ICSI) and the clinical parameters of their neonates. Design: Prospective double-centric randomized study which randomized by computer. Setting: International Islamic Center for Research and Population Studies Al-Azhar University and private infertility center from November 1, 2012 to December 31, 2015. Main Outcome Measure(s): Live birth was the main treatment outcome while the main outcome for the neonates was neonatal body weight (NBW). Result(s): With adjusting of confounders, this study showed that in ICIS cycles, couples with a female BMI ≥ 25 kg/m2 had a significantly higher odds of abortion and a significantly lower odds of live birth than couples with both male and female BMI < 25 Kg/m2. The neonatal body weight of singletons was significantly higher when their parents’ BMIs were greater; while, there are no significant differences were obtained in the NBWs of twins. Conclusion: Live births conceived via ICSI were negatively affected by increased maternal BMI while not affected by paternal BMI. The neonatal body weights of singletons increased with paternal BMI which did not significantly affect the NBWs of twins.

Keywords: To investigate intracytoplasmic sperm significantly higher odds NBWs of twins.