EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EVALUATION OF SYNERGISTIC ANTIULCER POTENTIAL OF ETHANOLIC EXTRACT OF BETA VULGARIS (TAPROOT) & FICUS RELIGIOSA (BARK) IN WISTAR RATS

*Rahul Arora and Neelanchal Trivedi

ABSTRACT

Objective: To authenticate the synergistic anti-ulcer potential of the ethanolic extract of Ficus religiosa bark and Beta vulgaris root aligned with in vivo pylorus ligation assay. Methods: The root and bark of the plants were extracted by ethanol. The ethanolic extract was subjected to evaluate its phytochemical profiles. Gastric ulcers induced in male wistar rats via ligating the pylorus part of stomach. The antiulcer activity was checked by formative and comparing the ulcer index in the experimental drug groups with that of the vehicle control and standards. Omeprazole was taken as standard drug. Dose was kept as 20 mg/kg as standard and 250 & 500 mg/kg for the plant extracts. The parameters taken to evaluate antiulcer activity were gastric juice volume, free acidity, total acidity and ulcer index. Result: The obtained results were: Percent Protection (71.02% & 68.45%), Mean Ulcer Index (0.31+0.13, 0.674 + 0.279 and 0.982 + 0.415), Gastric volume (2.13 + 0.139, 2.86 + 0.101 and 3.55 + 0.194), Gastric pH (4.25 + 0.140, 3.80 + 0.201 and 3.67 + 0.098), Free Acidity (29.99 + 2.904, 69.01 + 2.03 and 63.21 + 2.994), Total Acidity (1.72 + 1.69, 35.98 + 0.44 and 72.87 + 0.244) for 20 mg/kg standard drug and 250 & 500 mg/kg of ethanolic extract of EEBV+EEFR. Conclusion: The Ethanolic extract represented a noteworthy decrease in gastric pH, free acidity and total acidity as while compared with ulcer control using Pylorus Ligation Model.

Keywords: Beta vulgaris, Ficus religiosa, Ethanolic Extract, Omeprazole, Pylorus Ligation.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 November 2021 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • EJPMR: NOVEMBER ISSUE PUBLISHED

    NOVEMBER Issue has been successfully launched on 1 November 2021.

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )