EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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 ICV - 79.57

Abstract

ANTIBIOTIC SUSCEPTIBILITY PATTERN OF PSEUDOMONAS SPECIES AT A TERTIARY CARE HOSPITAL IN CENTRAL INDIA.

Tore R. P*, Lichade S. B and Shrikhande S. N.

ABSTRACT

Introduction: Pseudomonas is widely distributed in nature. Intrinsic resistance to numerous antibiotics contribute to their virulence. Aims & Objectives: To isolate the Pseudomonas species from different clinical specimens and to study their antibiotic susceptibility pattern. Material & Methods: Study was conducted in Department of Microbiology, Indira Gandhi Govt. Medical College, Nagpur from August 2011 - August 2013. Pseudomonas isolates were processed to species level by standard procedures and antibiotic susceptibility was done according to CLSI guidelines 2011. Observations & Results: A total of 210 Pseudomonas strains were isolated and maximum 44% were from pus. Amongst them, 95% were P. aeruginos ,2.4% were P. putida, 1.4% were P.stutzeri and 0.95% were P. fluorescens. Amongst the 200 P . aeruginosa, least resistance was found to colistin (2.5%) and imipenem (21%) followed by piperacillin-tazobactum (25%) and amikacin (27%). Resistance to cephalosporines, aminoglycosides, tobramycin and netillin was in the range of 30 – 35%. Ciprofloxacin was 52% and norfloxacin was 67% resistant. Metallo-betalactamase (MBL) production was observed in 12% isolates. The Pseudomonas isolates other than P. aeruginosa, were more sensitive as compare to P. aeruginosa. They were 100% sensitive to colistin and imipenem followed by 80% sensitivity to piperacillin -tazobactum, 70% to amikacin & gentamycin, 60% to tobramycin & netillin and 50% to cephalosporines, quinolones and aztreonam.

Keywords: Pseudomonas species, antibiotic resistance, metallo-beta lactamase.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia