ANTIBACTERIAL ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF Crocus sativus (SAFFRON) AGAINST MULTI- DRUG RESISTANT PATHOGENS
Dr. P. Venkatachalam*, Jyothiprabha V. and V. Anbumalar
ABSTRACT
The wide use of antibiotics in the treatment of bacterial infections has led to the emergence and spread of resistant strains. This present study was designed to investigate the preliminary phytochemical and antibacterial activity of saffron extracts against multi- drug resistant pathogens. The antibacterial activity of these extracts was checked against methicillin resistant Staphylococcus aureus, vancomycin resistant enterococcus and Escherichia coli by agar well diffusion method. The phytochemical screening of different solvent extracts of saffron revealed the presence of various secondary metabolites glycosides, saponin, steroids, flavonoids, terpanoids and tannins.
Keywords: Saffron, vancomycin resistant enterococcus, methicillin resistant Staphylococcus aureus, phytochemical, glycosides, Crocus sativus.
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