( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



*Dr. Rajdeep Saha MD, Dr. Apoorbaa Roy, Dr. Dipika Menon Mukherjee, Dr. Rajyasri GuhaThakurta MD.


Dengue is one of the most important arboviral infections prevalent in India. Dengue virus belongs to the genus flavivirus and family flaviviridae. The principle vector is Aedes aegypti. The disease is caused by any of the five serotypes DENV 1, DENV 2, DENV 3, DENV 4 and DENV 5.This present study has been planned to observe the co-infection of an individual with serotypes DENV 2 and DENV 3 and assess the clinical complications arising due to this co-infection. A total of 4337 blood samples were collected from patients who were grouped into: fever less than 5 days and fever more than 5 days. Serum from these samples was tested using ELISA: NS1 (for fever <5days) and MAC (for fever >5days). The samples which tested positive were further tested using PCR for identification of serotypes. Total no. of samples taken was 4337. Out of which 1401 (32.3%) samples tested positive with ELISA (NS1/MAC). On performing PCR 1050 (74.9%) samples showed infection with a single serotype and 351(25%) samples showed bands in two or more regions indicating co-infection with multiple serotypes. Out of which 237 (67.5%) showed co-infection with DENV 2(Dengue virus type 2) and DENV 3(Dengue virus type 3) and the rest i.e. 114 (32.4%) tested positive for co-infection with other serotypes. Amongst these 237 cases: 228 developed DHF (Dengue Haemorrhagic Fever) and 09 developed DSS(Dengue Shock Syndrome). Hence we see in this outbreak of dengue there is increased incidence of complication when there’s a co-infection with DENV2 and DENV3.

Keywords: Dengue, Dengue virus type 2(DENV 2), Dengue virus type 3(DENV 3), ELISA.

[Full Text Article]



  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 November 2021 Issue has been Published, Kindly check it on


    NOVEMBER Issue has been successfully launched on 1 November 2021.

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )