( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



*Dr. Omesh Kumar, Dr. Burhan Memon, Dr. Bilal Razaque Memon, Dr. Raheela Hassan, Dr. Amerta, Dr. Sanya Badar


Objective: To study the acanthosis nigricans (AN) as marker of β-cell function and insulin resistance in type 2 diabetic subjects. Study design: Observational study. Place and duration: Department of Medicine, Liaquat University of Medical and Health Sciences Jamshoro/Hyderabad from March 2016 to September 2016. Subjects and Methods: A sample of 70 type 2 DM subjects was divided into 2 groups with and without AN. Random and fasting blood glucose, fasting insulin, HbA1c, blood lipids, serum creatinine and bilirubin were detected and HOMA-IR model was calculated on computer. Data was analyzed on SPSS 22.0 (USA) software at 95% confidence interval (P ≤ 0.05). Results: Type 2 diabetics with acanthosis nigricans showed association with insulin resistance. The %β-cell function and %S (insulin sensivity) showed negative correlation and HOMA-IR (insulin resistance) showed positive correlation with acanthosis nigricans. Systolic and diastolic BP, random and fasting blood glucose, fasting insulin, HbA1c, triglycerides, LDLc, HDLc, and total cholesterol showed significant derangement in type 2 diabetics with Acanthosis nigricans. Conclusion: The present study proposes the acanthosis nigricans is a marker of insulin resistance which may be utilized in clinical practice and the HOMA-IR can serve as a marker of insulin resistance.

Keywords: Acanthosis nigricans, Insulin resistance, ?-cell function, Diabetes mellitus.

[Full Text Article]



  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 November 2021 Issue has been Published, Kindly check it on


    NOVEMBER Issue has been successfully launched on 1 November 2021.

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    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )