EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

COMPARATIVE EVALUATION OF ANTIMICROBIAL EFFICACY OF 0.2% CHLOROHEXIDINE GLUCONATE AND FENNEL SEED EXTRACT AGAINST STREPTOCOCCUS MUTANS AND LACTOBACILLUS ACIDOPHILUS-AN IN VITRO STUDY.

Dr. Parul Bhatnagar*, Dr. Ravinder Kaur Gulati, Dr. Pranav Gupta and Dr. Kumar Nilotpal

ABSTRACT

Objectives: The aim of this present study was to evaluate and compare antimicrobial efficacy of chlorohexidine gluconate and fennel seeds against streptococcus mutans and lactobacillus acidophilus. Study design: A total of six agar petri dishes for Streptococcus mutans and Lactobacillus acidophilus were prepared. The methanolic extract of fennel seed and 0.2% chlorohexidine were incoluted on the each petri dishes prepared separately for tested species and incubated at 37ºC for 24 hours. Zone of growth inhibition for each extract was measured in millimeters using antibiotic inhibiting zone measuring scale. Each extract was tested three times. The results was subjected to statistical analysis. Results: 0.2% Chlorohexidine showed the maximum zone of inhibition against S.mutans and Lactobacillus acidophilus. Fennel seeds also inhibited the growth of micro organism but to a lesser degree than 0.2% chlorohexidine gluconate. Conclusion: Chlorohexidine and fennel seed are effective in inhibiting the growth of cariogenic bacteria like Streptococcus mutans and Lactobacillus. Therefore, both herbal and chemical agents can be effectively used to reduce pathogenic oral microflora.

Keywords: Chlorhexidine gluconate, Fennel seeds, Streptococcus mutans, Lactobacillus acidophilus, Inhibition zone.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )