EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

ANTIOXIDANTS STATUS OF ACUTE ISCHAEMIC STROKE SUBJECTS IN SOKOTO, NIGERIA.

Isa, S.A., Wali U.*, Yusuf, S., Balarabe, S.A. and Bilbis L.S.

ABSTRACT

Acute ischaemic stroke (AIS) is characterized by elevated levels of oxidative stress indices and declined antioxidant defences. Increased oxidative stress is thought to play a critical role in the development of AIS and its associated complications. We investigated malondialdehyde (MDA), BP, FBS, SOD, GPx, CAT, vitamins (A,C and E), Zn, Cr, Cu, Mn and Se of 79 AIS subjects admitted in Neuro Medical Ward of Usmanu Danfodiyo University Teaching Hospital (UDUTH),Sokoto,Nigeria and the results compared with 20 non-acute ischaemic stroke (NAIS) subjects of comparable age and social status. The results suggested significant increase (p<0.05) levels of MDA, BP, FBS and significant decrease (p<0.05) levels of vitamins A, C and E, SOD, GPx, CAT, Zn, Cr, Mn and Se and non significant decrease (P>0.05) level of Cu in AIS subjects compared with NAIS subjects. It is concluded that acute ischaemic strokes in the study area have depletion of antioxidant defense mechanism, an indication that the AIS subjects are predisposed to increased oxidative onslaught.

Keywords: Antioxidants, acute ischaemic stroke, oxidative stress.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )