EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

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 ICV - 79.57

Abstract

“EFFICACY OF DEXMEDETOMIDINE AND FENTANYL AS ADJUNCTS TO EPIDURAL BUPIVACAINE FOR LOWER ABDOMINAL SURGERIES.”

Sofi Khalid*, Tantry Tariq Gani, Mir Waheed, Bhat Khairat

ABSTRACT

Background and Aims: This prospective, randomized, double blind study was undertaken to establish the effect of addition of fentanyl or dexmedetomidine, as an adjunct to epidural bupivacaine in lower abdominal surgeries. Materials and Methods: Ninety ASA (American Society of Anesthesiologists) class I and II patients undergoing lower abdominal surgeries were enrolled to receive either saline (Group BS) or fentanyl (Group BF) or dexmedetomidine (Group BD) along with epidural bupivacaine for surgical anesthesia. All the study subjects received an epidural anesthesia with 20 ml of 0.5% bupivacaine along with either saline 2ml (Group BS) or fentanyl 1mcg/kg (Group BF) or dexmedetomidine 1.0 μg/kg (Group BD). The onset of motor and sensory block, duration of block, hemodynamic parameters, and adverse events were monitored. Results: Analgesia in the postoperative period was better in Group BD, together with duration of sensory and motor blockade.However incidence of sedation was more in the BD group. Conclusion: Hence, addition of Dexmedetomidine to epidural bupivacaine can be advantageous with respect to early onset of both sensory and motor block and increased duration of motor and sensory blockade and arousable sedation.

Keywords: Dexmedetomidine, Epidural, Fentanyl and Bupivacaine.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia