EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

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 ISSN 2394-3211

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Abstract

PHYSIOCHEMICAL SCREENING OF MARKER ANTHRAQUINONES AND DERIVATIVES FROM THE PENTAS LANCEOLATA (FORSS. K.) DEFLERS LEAVES

*Pragati Kumar, Dr. Ashish Kumar Sharma and Dr. Prabodh Shukla 

ABSTRACT

Pentas lanceolata (Forssk.) Deflers belonging to family Rubiaceae, is a most common plant widely used names are “Egyptian Star Cluster” or “Pentas”. As a decorative plant, it has been spread all over the tropical and subtropical regions. The Preliminary Phytochemical screening with different solvent extract like Methanol, Chloroform and water with the Leaves of Pentas lanceolata plant showed Presence of glycosides, sterols, flavonoids, triterpinoids, alkaloids, carbohydrates and resins. Chromatographic separation of the methanolic extract yielded nine anthraquinones and derivatives, of which Rubiadin-1-methyl ether-3-O-β-primeveroside, Rubiadin-1-methyl Ether, Damnacanthol (3-hydroxy-2-hydroxymethyl-1-methoxy-9, 10-anthraquinone), Rubiadin (1,3-dihydroxy-2-methyl-9,10- anthraquinone) and Lucidin-ω-methyl ether (1,3-Dihydroxy-2-methoxymethyl-9,10-anthraquinone) were separate out by Preparative TLC and screened out by different spectroscopic techniques. The one steroidal compound was also isolated and was identified as (24S)-24-Ethylcholesta-5-(E)-22-dien-3β-ol (β-Stigmasterol).

Keywords: Methanol, Anthraquinones, Sterols, Preparative TLC, NMR, ?-Stigmasterol.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia