EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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 ICV - 79.57

Abstract

CORRELATION OF CENTRAL CORNEAL THICKNESS ON OCT AND PACHYMETRY IN GLAUCOMA PATIENTS

*Dr. Priyanka Kolhe, Dr. Chandni Karole, 3Dr. Shivam Goyal and Dr. Deepti Mujumdar

ABSTRACT

BACKGROUND AND AIM: Central corneal thickness (CCT) measurement has become an important test in the diagnosis and management of glaucoma. Currently, ultrasound corneal thickness measurement (pachymetry) is the most frequently used clinical technique and the gold standard to assess CCT. Newer instruments are currently available including the optical coherence tomography (OCT) instrument. The aim of the present study was therefore to evaluate the accuracy of the CCT measurements, both with the OCT and ultrasound pachymetry (USP), in patients suffering from glaucoma. METHODS: Cross-sectional study, Ophthalmological examination was performed before including patients in the study. Visual acuity by snellens chart, IOP measurements by goldmann applation tonometer , optic nerve status by 90D lens slit lamp biomicroscopy, gonioscopy, Humphrey visual fields (HFA, 24–2), and presence or absence of exfoliation were noted after pupil dilatation under slit lamp examination. Glaucoma was defined as patients who had at least two repeatable Humphrey visual fields showing glaucoma damage using the software 24–2, and with the optic nerve showing typical glaucoma damage. RESULTS: 48 eyes of 25 patients were included. The average age was 64 ± standard deviation (SD) 10.88, the average pachymetry value with OCT was 536 ± 29 μm, and the average pachymetry with USP was 532 ± 32μm. The differences between OCT and USP were not significant (t-test, p = 0.32). The intraclass correlation coefficients were, for OCT, 0.99 [confidence interval (CI): 0.98–0.996], and for USP, 0.97 (CI: 0.95–0.98). CONCLUSIONS: OCT and USP both showed high accuracy in pachymetry measurements. OCT Might be used as a substitute for pachymetry, if USP is not available.

Keywords: Optical coherence tomography, USP pachymetry, humphery perimetry, central corneal thickness, glaucoma.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )