EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EVALUATION OF PRELIMINARY ANTIBACTERIAL ACTIVITY AND UV-SPECROSCOPIC ANALYSIS OF MICHELIA CHAMPACA (L.)

T. Lavanya and T. Ananthi*

ABSTRACT

The aim of the present study was undertaken to appraise the UV-VIS analysis and antibacterial activity of flowers of Michelia champaca. The phytochemical analysis revealed the presence of carbohydrate, alkaloids, terpenoids, flavonoids, tannins, steroids and phenols. The UV-VIS profile of flower extract showed the peaks at 281.1 nm and 215.6 nm with the absorption of 2.397 and 4.040. The antibacterial activity of flower extract against gram positive (Staphylococcus aureus and Bacillus subtilis) and gram negative bacteria (E.coli) were tested by using disc diffusion method. Ampicilin was used as standard. The results obtained shows that the extract expressed remarkable antibacterial activity with zone of inhibition ranging from 9 to 19 mm. Maximum inhibition zone was recorded with Bacillus subtilis (19.6 mm) while minimum inhibition zone was recorded for E.coli (9.37mm). The antibacterial activity increased linearly with increase in concentration of the extract. The antibacterial activity of Michelia champaca was due to the presence of various bioactive constituents present in the flower extract. The results provide a support for the use of this plant in traditional medicine and it is a potential antiseptic source for prevention and treatment of bacterial infections.

Keywords: Michelia champaca, UV-Visible, ampicilin, antibacterial activity.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )