EFFICACY OF INTRAVENOUS FLUID ON PREVENTION OF POST-OPERATIVE NAUSEA AND VOMITING FOR THYROIDECTOMY PATIENTS AT AYDER COMPREHENSIVE SPECIALIZED HOSPITAL MEKELLE UNIVERSITY, NORTHERN ETHIOPIA

Kore Menjie Benwu*, Hagos Gebregziabher Gebremedhinand and Dessaleng Belay Mihrete

ABSTRACT

Background: Nausea and vomiting are commonly happening complications after thyroidectomy surgery. Pulmonary aspiration, fluid and electrolyte disturbances are the early complications of nausea and vomiting which could be happen after thyroidectomy surgery. Although there are many anti-emetics drugs are available but benefit is observed on few of them and some of the drugs have life threaten complications. Objective: The aim of this study was to assess the efficacy of bolus intravenous fluid for the prevention post-operative nausea and vomiting at, Mekelle University Ayder comprehensive Referral Hospital. Methodology: Cohort study was carried out at Mekelle University Ayder comprehensive Specialized Referral Hospital from August 30–December 30, 2016 using probability sampling technique. Result: Incidence rate of nausea and bolus intravenous preoperative fluid administration was significantly associated in which incidence of nausea in non-exposed group was 2 times more likely to happen when compared to patients in exposed group in late postop time. Number of vomit was also statically associated with the pre-operative fluid administration of the patient (p<0.05). Regarding to anti-emetic used patients assigned in the non-exposed group were subjected for antiemetic 3 times more than patients those who were assigned in the exposed group in late postop time. Conclusion and recommendation: The incidence rate of post-operative nausea and vomiting and anti-emetic used in each phase of post-operative period was highly associated with pre-operative administration of intravenous fluid in the bivariate analysis, further studying mainly addresses on amount of bolus fluid should be considered.

Keywords: Anesthesia, postoperative, fluid, preoperative.