A CRITICAL REVIEW ON CURRENT THERAPY ON ULCERATIVE COLITIS
*D. Bharath Kumar, Kolavali Yalla Reddy, Suruchi Samparna Acharya, Ch. Saritha and P. Venkatesh
Ulcerative colitis is an inflammatory chronic disease primarily affecting the colonic mucosa. The extent and severity of colon involvement are variable. Ulcerative colitis is one of the most prevalent gastrointestinal disorders, which affects approximately 5-10% of people during their life. In recent years, abundant work has been carried out on herbal medicine to clarify their potential efficacy in ulcerative colitus prevention or management. A number of medicinal plants such as Amomum subulatum, Scoparia dulcis, Jasminum grandiflorum, Davilla rugosa, Kielmeyera coriacea, Larrea divaricata, Qualer grandiflora, Mammea Americana, Anacardium occidentale, Ocimum sanctum, Azadirachta indica, Acorus calamus, Gingko bioloba, Curcuma longa, Withania somnifera, Polygala tenulfolia etc. Despite of all the advances in modern and orthodox medicine, traditional medicine still plays a significant role in the lives of many people suffering with ulcerative colitus. These plants provide leads to find therapeutically useful compounds, thus more efforts should be made towards isolation and characterization of the active principles and their structure activity relationship and produce better drugs for the treatment of ulcerative colitis with fewer side effects.
Keywords: Chronic disease, Herbal medicine, Curcuma longa, Orthodox medicine.
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