EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

ELECTROLYTE CONCENTRATION IN ALBINO RATS FED WITH PIMENTA DIOICA BERRIES

*Kalio Ibiene Sarah, Joshua Marcella Tari and Stephen Fortune Ibinabo

ABSTRACT

Background: pimenta dioica is used in the eastern region of Nigeria for culinary purposes. This tradition is passed down from generation to generation by the natives of the Niger Delta. Long term effect of pimenta dioica on electrolyte level in Niger Delta region of Nigeria is yet to be determined. This study was conducted, to determine electrolyte concentration in albino rats fed with pimenta dioica berries. Materials and Methods: Twenty albino rats Weighing between 150-180g were grouped into four groups of five rats labeled control, A,B and C. Control group were fed only commercial pellets. Group A received 10g of pimenta dioica berries, Group B received 20g pimenta dioica berries while group C received 30g of pimenta dioica berries daily for 21days. The animals were slaughtered after 7, 14 and 21days and blood samples collected into well labelled heparinized bottle for electrolyte estimation. Electrolyte was estimated using Ion Selective Electrode. Result: The result for electrolyte showed that there was no significant elevation in test parameters; sodium (P > 0.05), potassium (P > 0.05), chloride (P > 0.05), bicarbonate (P > 0.05) and anion gap (P > 0.05) when compared with control. Conclusion: The results in this study suggest that pimenta dioica berries may not predispose consumers to electrolyte imbalance and metabolic acidiosis. However caution should be taken in consumption of pimenta dioica berries in high concentration.

Keywords: Pimenta dioica, Electrolyte, Anion gap, Ikum spice.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia