A COMPREHENSIVE REVIEW ON NOVEL DRUGS APPROACHES IN TYPE 2 DIABETES MELLITUS
Prajakta Kale, Anand P. Khadke*, Anuradha A. Khadke and Avinash M. Bhagwat
Diabetes mellitus belongs to the most rapidly increasing diseases worldwide. Approximately 90–95% of these patients suffer from type 2 diabetes mellitus. Type 2 diabetes mellitus (DM) is a disorder characterised by insulin resistance and a progressive decline in pancreatic beta-cell function associated with increasing hyperglycemia. This review will briefly summarize novel type 2 anti-diabetic drugs.Their suitability as ‗ideal anti-diabetic drugs‘ will be discussed. The aim of this article is to present an overview of all the available novel type 2 antidiabetic drugs according to the different classes, their mechanisms of action and pharmacological profiles, and to assist physicians to make the correct choice for their patients. This article is written about the need for novel drug delivery systems in the treatment of type 2 diabetes.
Keywords: Type 2 diabetes, Qtern , Lixisenatide ,Soliqua , Invokamet, Xultophy.
[Full Text Article]