EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

PREVALENCE OF MICROALBUMINURIA IN NON-DIABETIC HYPERTENSIVE PATIENTS AND ITS ASSOCIATION WITH LEFT VENTRICULAR HYPERTROPHY IN A TERTIARY CARE HOSPITAL

Dr. Mohan Kashinkunti and Dr. Aneesh T.*

ABSTRACT

Introduction: - Essential hypertension is one of the commonest medical problems in the general population and is one of the most important modifiable cardiovascular risk factors. Left ventricular hypertrophy also has a prognostic value in patients with Hypertension that strongly correlates with adverse cardiovascular outcome. Microalbuminuria is a state of increased vascular permeability particularly in the kidney. It is an easily measured marker of endothelial dysfunction and low grade inflammation. This study was designed to determine whether an association exists between urine microalbumin and left ventricular hypertrophy in non-diabetic hypertensive patients. Aim: - To study the prevalence of microalbuminuria in non-diabetic hypertensive patients and determine the relationship between microalbuminuria and left ventricular hypertrophy. Methods: - 120 non-diabetic, hypertensive patients aged more than 30 years who attended General Medicine outpatient clinic and who were admitted during the study period were enrolled in this prospective study. Results: - The mean age of the study population was 55.15±10.17 years, with most patients aged between 51-60 years. 55% of the patients showed evidence of left ventricular hypertrophy, among these patients 85.67% of them had microalbuminuria. In this study, majority of the patients (60%) had stage 2 hypertension, as the severity of hypertension at presentation increased, prevalence of microalbuminuria also increased and this correlation was statistically significant. Conclusion: - This study demonstrates a high prevalence of microalbuminuria and Left ventricular hypertrophy which are independent predictors of cardiovascular morbidity and mortality in patients with essential hypertension. Screening for urine albumin excretion should be extensively adopted in clinical care as it is a relatively simple, readily available and cost effective test especially in resource limited settings where ECHO services are not readily available.

Keywords: Hypertension, Left ventricular hypertrophy, microalbuminuria, cardiovascular disease.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )