EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EXTRACT OF MORINGA OLEIFERA PLANT IN ALBINO WISTAR RATS”.

Dr. Abhijeet Bhagat*, Dr. Alimuddin Shaikh and Dr. Shaikh Huzaif

ABSTRACT

Introduction: Moringa Oleifera is widely found in Asian subcontinent and it has been used as an analgesic and anti-inflammatory in Indian folk medicine. In this study we compared the analgesic effects of Moringa Oleifera Ethanolic extracts with standard drug diclofenac in Wistar Albino Rats by hot plate method. Methods: Male Wistar albino rats were divided into 5 groups and administered placebo (saline), diclofenac and 3 groups of Moringa Oleifera using 100mg/Kg, 200mg/Kg and 400mg/kg doses. Results: Moringa Oleifera 400mg/Kg produced significant anti-nociceptive action by increasing prolongation of reaction time at 30 min, 60 min and 120 min.Moringa Oleifera (200mg/Kg) also produced significant antinocipetive action by prolongation of reaction time at 30 min, 60 min and 120 min. The Standard drug Diclofenac increased the prolongation of reaction time sustained all throughout the period Conclusion: Ethanolic extracts of Moringa Oleifera leaves exhibits significant anti-nociceptive activity by hot plate model in a dose dependent manner. However the amount of anti-nociceptive action produced was lesser as compared to standard drugs like Diclofenac.

Keywords: Anti-nociception, Diclofenac, Moringa Oleifera.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )