EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

THYROID FUNCTION IN SUDANESE GOLD MINERS WITH CHRONIC MERCURY EXPOSURE

Eltayeb Tayrab*

ABSTRACT

The aim of the study was to assess the thyroid functions in traditional gold miners in the River Nile State- Sudan; including thyroid stimulating hormone (TSH), total and free thyroxine (TT4, FT4) and total plus free triiodothyronine (TT3, FT3); as continuation of the studies on health effect in traditional gold miners in Sudan. Material and methods: blood samples were collected from 83 Sudanese miners working in traditional mining sites, beside 50 healthy volunteers from Khartoum State, as control group. Serum thyroid hormones were measured using (ELISA). Data were analyzed using IBM SPSS Statistics version 20. Results: The mean serum levels of TSH, TT3, FT3, TT4 & FT4, among artisanal gold miners was (5.13 μIU/ml, 1.16 ng/dl, 1.34 pg/ml, 86, 34 pmol/l and 6.41 ng/dl); versus (2.40 μIU/ml, 1.47 ng/dl, 3.12 pg/ml, 72.62 pmol/l, and 12.51 ng/dl) in the control group; respectively. There was significant decrease in serum TT3, FT3 and FT4 when compared to their control (P.value= 0.004, 0.000, 0.000) respectively; while there was a significant increase in serum TSH and TT4 (P.value= 0.000, 0.002) respectively. Conclusion: In traditional gold miners working in Abuhamed; thyroid stimulating hormone and total thyroxine significantly increase; while total triiodothyronine, free triiodothyronine and free thyroxine significantly decrease.

Keywords: thyroid, hormones, serum, gold miners, mercury, Sudan.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia