EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EVALUATION OF THE HYPOGLYCEMIC AND ANTI-HYPERGLYCEMIC ACTIVITIES OF AQUEOUS AND HYDROETHANOLIC EXTRACTS OF ERYTHROCOCCA ANOMALA LEAVES IN RAT.

Miezan Bile Aka Patrice*, Kouakou Sylvain Landry, Aka Francis Beranger Angelo,
Kouakou–Siransy Giselle, Droucoula Guillaume Cyril and Yapi Houphouet Felix

ABSTRACT

Erythrococca anomala (Euphorbiaceae) is an annual medicinal plant, widely used in traditional medicine in Cote d’Ivoire and sub-Saharan Africa as an anti-inflammatory, laxative and purgative. In the present work, the aim was to evaluate the hypoglycemic and anti-hyperglycemic activity of the aqueous and hydroethanolic extracts of the leaves of this plant in the rat. The blood glucose was determined using a glucose reader Test strips). Administered orally at doses of 100 and 200 mg / kg body weight the extracts induce dose-dependent hypoglycemia in the rat. These aqueous and hydroethanolic extracts at a dose of 200 mg / kg body weight significantly reduced the hyperglycemia caused by administration by glibenclamide, the reference anti-hyperglycemic molecule (10 mg / kg body weight). Oral glucose at a dose of 5 mg / kg body weight to the rat.

Keywords: Erythrococca anomala, Euphorbiaceae, Hypoglycemic, Anti-hyperglycemic, glibenclamide.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )