( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Dr. Muhammad Ayoob Memon*, Dr. Zaid Feroz Memon, Dr. Abeer Rafique, Dr. Muhammad Haroon Mujtaba, Dr. Ramsha Fazal and Dr. Rajesh Kumar


Objective: To determine the association of serum immunoglobulin E (IgE) and vitamin D3 in bronchial asthma. Study Design: Case control study. Place and Duration: Department of Medicine -Liaquat University of Medical and Health Sciences Hospital from January 2015- September 2016. Subjects and Methods: A sample of 100 subjects was divided into 50 cases of bronchial asthma and 50 controls. Ethical permission and consent was taken. Venous blood samples were collected. Blood complete picture, serum IgE and vitamin D3 were estimated. Performa was used for data collection. Statistix 8.1 version (USA) was used for data analysis at 95% confidence interval (P≤0.05). Results: Mean ± SD age noted in controls and cases was 52.73±7.39 and 54.42 ±5.89 years respectively. Blood Eosinophils in the in cases were noted as 5.85 ± 2.32 compared to 3.38 ± 1.72 % per μL in controls (P=0.0002). Controls showed Vitamin D3 35.24±11.74 ng/dl vs. 22.06±13.6 ng/dl in cases (P=0.0003). Serum IgE in controls and cases was noted as 80.60±15.95 and 551.5±372.31 IU/ml (P=0.0001). Serum IgE and blood eosinophils showed negative correlation with vitamin D3 (r= -0.485, P= 0.0001 and r= -0.75, P= 0.0001 respectively). Conclusion: The present study shows raised serum IgE and low vitamin D3 in bronchial asthma. Serum IgE shows negative association with vitamin D3.

Keywords: Bronchial Asthma, IgE, Vitamin D3, Eosinophils.

[Full Text Article]



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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database