EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

FIBRINOGEN AS THE BIOMARKER OF SUBCLINICAL ATHEROGENESIS IN ADULT MALE SMOKERS.

*Dr. A.G. Thivyah Prabha

ABSTRACT

Smoking of cigarettes is one of the major health hazards of the world population as it is contributing to the cardiovascular diseases and to the increasing proportion of the sudden deaths. Fibrinogen is one of the independent & significant marker of cardiovascular mortality. The aim of the study is to identify the earlier marker of atherogenesis in healthy adult male smokers for the better risk prediction and screening purpose. 60 adult healthy men of age group 19-49 years were enrolled. 30 smokers & 30 non- smoker. Smokers were compared with the non-smokers by doing the blood tests which included blood glucose, lipid profile and Fibrinogen. Smokers had significantly higher levels of total serum cholesterol [245.03±72.82 vs160.07±21.39 p<0.000], LDL levels [149.17±48.87vs.98.67±14.93p<0.000] and triglyceride levels [152.43±52.40vs. 94.83±17.75p<0.000]. HDL levels were low in smokers. Fibrinogen levels were higher in smokers [644.20±231.38vs300.20±49.91p<0.000] respectively. There is a positive correlation between the duration of smoking Fibrinogen levels [r=0.917p<0.000]. This case control study shows significantly higher Fibrinogen levels in smokers in proportion to the duration & amount of cigarettes smoked pre day, as compared to the non-smokers. Thus hsCRP & Fibrinogen can be used as the bio markers of sub-clinical atherogenesis screening in healthy adult male smokers.

Keywords: Fibrinogen, Atherosclerosis, Smokers.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )