EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EFFECT OF GREEN TEA ON COMPREHENSIVE METABOLIC PANEL AND HYPERLIPIDAEMIA DUE TO NICOTINE EXPOSURE IN WISTAR ALBINO RAT

Marwan M. Draid* and Khalid M. Ben-Elhaj

ABSTRACT

Background: Nicotine has a long and storied history in physiology and pharmacology. We investigated the effects of nicotine on comprehensive metabolic panel (CMP) and lipid profile within male Wistar albino rats and interaction of aqueous extract of green tea. Methods: Forty male wistar albino rats were divided into four groups of ten, controls without any treatment, green tea, nicotine, and green tea + nicotine. Over a 28 day period the control received daily subcutaneous does of saline (10 ml) and drank only water, green tea group received subcutaneous does of saline (10 ml) and drank only green tea, the nicotine group received subcutaneous does of nicotine in a saline carrier solution (10ml saline with 3mg/kg body weight of nicotine) and drank only water, and green tea + nicotine received subcutaneous does of nicotine in a saline carrier solution (10ml saline with 3mg/kg body weight of nicotine) and drank only green tea. At the end of the experiment period, blood samples were collected for biochemical analysis. Results: There were no differences between the control and green tea only groups for any parameter. The nicotine group had comprehensive metabolic panel and lipid profile concentrations significantly (P < 0.05) changes compare to control, and Green tea only groups. However using green tea with nicotine had reversed these changes. Conclusions: This study showed that injecting nicotine subcutaneously had effect on comprehensive metabolic panel and lipid profile which eliminated by aqueous extract of green tea on Wistar albino rats.

Keywords: Green tea, Nicotine, Comprehensive metabolic panel, Lipid profile.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )