EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

INVITRO ANTI-ARTHRITIC EFFECT OF THE LEAVES OF CASSIA FISTULA LINN.

Mahendar Boddupally*, Dr. S. Shobha Rani, A. Thanga Thirupathi, K.N.V. Rao, R. Vasanthi

ABSTRACT

The objective of present work is to study the in-vitro anti-arthritic activity of Cassia fistula linn leaf, a traditional plant of Telangana, India. The ethanolic extract of Cassia fistula linn leaf (EECFL) was studied for In-Vitro anti-arthritic activity by bovine serum protein denaturation method. The activity of ethanolic extract of CFL was compared with standard anti-inflammatory drug Diclofenec. It showed 18.3%, 29.7%,44.4%,69.2%,81.5%,93.1% inhibition of denaturation @ 100,200,400,600,800,1000mcg/ml of bovin serum whereas, standard diclofenac @ 100, 200, 400,600,800,1000 mcg/ml showed 16.8%,27.4%,51.2%, 63.4%,70.6%,89.9% inhibition of denaturation of bovin serum. It was found that ethanolic extract of Cassis fistula linn leaves was more potent in inhibition of egg albumin denaturation than diclofenac. Finally, from results it can be concluded that Cassia fistula linn a traditional plant of Telangana posses good Invitro anti-arthritic activity. By further extensive research, we can explore the medicinal value of Cassia fistula linn leaf.

Keywords: Cassia fistula linn, Arthritis, Protein denaturation, Diclofenac sodium, Bovine serum albumin.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database