EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

SERUM ZINC AND COPPER LEVELS IN HIV POSITIVES PATIENTS

Brahma Reddy. Malapati, Dr. Nadeem, Ms. Bhavita Patel, Dr. Rita Shah, Dr. Nillawar AN

ABSTRACT

Background: Micronutrient deficiencies, which are commonly observed with advanced HIV disease, have been associated with higher risks of HIV disease progression and mortality. Objectives: The Aim of the present study was to assess Serum Zinc and copper levels among IV Patients and correlate it with age, sex and duration of infection. Methodology: Descriptive cross-sectional study was conducted in the Dhiraj hospitals, Sumandeep vidypeeth university, SBKS Medical College, blood samples obtained from 150 HIV sero-positive individuals and age and gender matched healthy controls were analyzed for zinc, and copper using spectrophotometer. Data were analyzed by Statistical computer software. Results: The (mean±SD) of Serum copper and zinc were (22.9±1.7mg/dl, 7.1±0.9mg/dl) in patients and (16.3±3.3 mg/dl, 11.5±3.0 mg/dl) in control group, respectively. The Serum Zinc level was significantly decreased in HIV patients (P value, 0.05) while Serum Copper level was significantly increased compared to healthy individual. There was strong negative correlation between Serum zinc levels and duration of HIV disease (r = -0.5, p value =0.00) and age of patients (r = - 0.58 p value = 0.01). There was weak positive correlation between copper level and duration of HIV disease (r =0.16, p value =0.223) and age of patients (r =0.4, p value =0.05). The differences in Serum copper and Zinc levels were insignificant between male and female in HIV patients (p value > 0.05). Conclusion: This study indicates that Zinc and copper levels are altered in HIV infected patients with more decreased Zinc level suspected with increased duration of HIV disease.

Keywords: Serum zinc, Serum copper, HIV.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia