EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

DEVELOPMENT AND ANTIMICROBIAL POTENTIAL OF SOAP BASED ON AQUEOUS EXTRACT OF LEAVES OF MORINDA MORINDOIDES (MORINDA, RUBIACEAE) AGAINST CUTANEOUS PATHOGENS.

TOURE Abdoulaye*, OUATTARA Karamoko, BAHI Calixte, DJAMAN Allico Joseph, & COULIBALY Adama

ABSTRACT

Different extracts of leaves of Morinda morindoides (Baker) Milne-Redh (Rubiaceae) showed interesting in vitro antimicrobial activities against pathogenics involved in cutaneous infections. The purpose of this investigations was to formulated soap based on aqueous extract of leaves of the plant as antimicrobial agent and tested it activity against 2 bacteria (Staphylococcus aureus and Pseudomonas aeruginosa) and 4 fungi (Candida albicans, Candida tropicalis, Trichophyton rubrum and Trichophyton mentagrophytes). The method of study was to developed soap (Soap S1) by incorporation of aqueous extract of M. morindoides as antimicrobial agent in formula of basic soap (Soap S0). Antimicrobial parameters (MIC and IC50) of 2 soaps (S0 and S1) against the above microorganisms strains were determined by agar both dilution and plate methods. All strains tested were inhibited by both types of soaps with values of MIC ranging between 62.50 – 31.25 mg/mL and 125.00 – 62.50 mg/mL respectively for soap S1 and soap S0. C. albicans was the least strain whereas T. mentagrophytes was most sensitive in the presence of 2 soaps. In comparison with control soap (S0), these results showed that aqueous extract of M. morindoides gave to soap S1 an effective antimicrobial power on tested microorganisms. This investigation is a part of valorization of previous work of our research team on extracts of M. morindoides. Thus this finding is a real hope in development of products to effectively prevent or fight microbial cutaneous infections.

Keywords: Morinda morindoides, aqueous extract, soap, antimicrobial potential, valorization, cutaneous infections.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia