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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Dr. Farukhuddin*, Dr. Pooja Devi, Dr. Rabia Waseem Shaikh, Dr. Bilal Razaque Memon, Dr. Raheela Hassan, Dr. Shahzore Gul


Objective: To analyze the Gamma Glutamyl Transferase (ϒ-GT) as predictive marker of carotid intima media thickness (CIMT) in type 2 Diabetic subjects. Study Design: Case control study. Place & Duration: Department of Medicine -Liaquat University of Medical and Health Sciences Hospital from November 2015- August 2016. Subjects & Methods: A sample of 40 healthy controls and 45 type 2 diabetics was selected through non-probability (purposive) sampling by prior inclusion and exclusion criteria. Serum ϒ-GT was estimated by enzymatic colorimetric test. Carotid artery was examined with a 7.5-MHz linear-array transducer (Siemens Acuson x300) sonography. Data was analyzed using the SPSS 22.0 (USA) and Graph Pad Prism at 95% CI (P≤ 0.05). Results: Carotid intima media thickness (CIMT) in controls and cases was noted as 0.52± 0.07 and 0.75± 0.071 mm (P=0.0001). Significant ϒ-GT difference was noted between controls and cases i.e; 34.98± 5.47 and 42.71± 6.49 U/L (P=0.001). The ϒ-GT showed positive correlation with CIMT (r= 0.615, P=0.0001). The ϒ-GT significantly predicted the CIMT by simple linear regression model (F= 50.37, P= 00001, R2 = 0.378). Conclusion: The present study reports the serum ϒ-GT was increased in proportionate to CIMT. Serum ϒ-GT may be used as a non-invasive, inexpensive and easily available marker for atherosclerosis.

Keywords: Gamma glutamyl transferase Carotid intima media thickness Atherosclerosis Diabetes mellitus.

[Full Text Article]



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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database