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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Dr. K. Sangeetha MD*, Dr. R. Mohandoss MD, Ajay V., Deepavarshini P. and Dr. G. Shiv Kumar MD 


Organophosphorus poisoning is a major public health problem in developing countries. In India, rate of suicidal poisoning with OPC ranges from 10.30 to 43.8%. Aim and objective: 1. To study the changes in serum levels of LDH and CK in patients with organophosphorus compound poisoning. 2. To correlate the severity of the poisoning with the levels of CK & LDH. Materials and Methods: In this prospective study we included 60 patients - 32 males and 28 females. The mean age of patients was 31.5 years. Based on Peradeniya Organophosphorus Poisoning (POP) score patients were divided into (42.5%) mild, (37%) moderate, (20%) severe cases. Results: A significantly increased serum CK, LDH levels in OPC poisoning cases than controls. The mean levels of CK and LDH is higher in severe POP score patients (CK =312.2±53.1 IU/L, LDH=690.1±42.5 IU/L) than moderate POP score patients (CK =291.4±75.7 IU/L, LDH=466.8±67.3 IU/L). The mean levels of CK and LDH higher in moderate POP score patients (CK =291.4±75.7 IU/L, LDH=466.8±67.3 IU/L) than mild POP score patients (CK =157.8±48.8 IU/L, LDH=266.7±29.5IU/L). conclusion: Early assessment the severity marker is very important reduce the mortality. CK, LDH levels can be an efficient biomarker and can predict the prognosis OPC poisoning.

Keywords: Organophosphorus Compound (OPC), lactate dehydrogenous (LDH), creatine kinase (CK) Peradeniya organophosphorus poisoning (POP).

[Full Text Article]



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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )