EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , Doi-Digital Online Identifier , ISSN National Centre , Zenodo Indexing , International CODEN Service, USA ,

ISSN (O) : 2394-3211

ISSN (P) : 3051-2573

Impact Factor: 8.158

ICV - 79.57

Abstract

EXPERIMENTAL EVALUATION OF ANTI-DIABETIC ACTIVITY AND ANTI HYPERLIPIDEMIC EVALUATION OF LEAF EXTRACTS OF SENNA ALATA IN ALLOXAN INDUCED DIABETIC RATS

Rama Swamy Nanna*, Archana Pamulaparthi, Vamshi Ramana Prathap, Mahitha Banala

ABSTRACT

Senna alata (Syn. Cassia alata) is an ethnomedicinal plant belonging to the family Fabaceae. A number of bioactive constituents which contribute to the medicinal properties are attributed to the species. The present study is aimed to evaluate the anti diabetic activity attributed to the species and also to evaluate the anti hyperlipidemic potential of the species using various standard experimental models available. Acute toxicity studies of aqueous leaf extracts of S. alata were performed upto a dose of 2500mg/kg bodyweight of rats and a dose of 200 mg/kg was selected for the present study. Aqueous leaf extracts of S. alata showed a significant (P<0.01) anti diabetic and anti hyperlipedimic potential in alloxan induced diabetic rats within 15 days of induction of diabetes and the antidiabetic potential of the species may be due to the presence of flavonoids.

Keywords: Senna alata, Alloxan induced diabetes, Anti Diabetic, Anti Hyperlipedemic.

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SJIF Impact Factor: 8.158

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New Issue Published
Its Our pleasure to inform you that, EJPMR 1 March 2026 Issue has been Published, Kindly check it on https://www.ejpmr.com/issue

EJPMR: MARCH ISSUE PUBLISHED
MARCH 2026 issue has been successfully launched on 1 MARCH 2026.

EJPMR: New Impact Factor 2026
EJPMR Impact Factor has been Increased from 7.065 to 8.158, for Year 2026

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EUROPEAN JOURNAL OF PHARMACEUTICAL AND MEDICAL RESEARCH