RAFT FORMING TABLETS: A NOVEL DRUG DELIVERY SYSTEM
Kanabar Vishvesh B*, Patel Vipul P, Doshi Sumit M.
In this article, a novel drug delivery system of GRDDS (Gastro retentive Drug Delivery System) named as Raft forming tablet is discussed. Drugs with narrow absorption window in the gastrointestinal tract have poor absorption. Therefore, gastro retentive drug delivery systems (GRDDS) have been developed, which prolong the gastric emptying time. Several techniques such as Rafting drug delivery system, low density systems, raft systems, mucoadhesive systems, high density systems, super porous hydrogels and magnetic
systems, have been employed. The Rafting drug delivery systems are useful approach to avoid this variability with increase the retention time of the drug delivery systems for more than 12 hours. Raft forming tablets are those forms which forms a gel like structure in presence of acidic environment of stomach which is known as Raft. So by this way numerous advantages and application are done by means of same dosage form.
Keywords: GRDDS, Gel Formation tablets, Rafting tablets, Novel Drug, Gastro retentive Drug Delivery System.
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