COMPARATIVE STUDY OF TIMOLOL MALEATE AND BRIMONIDINE TARTARATE IN GLAUCOMA MANAGEMENT IN A TERTIARY CARE HOSPITAL

A. A. Mohamed Yasir Arafath*, Fibimol Baby, A. Helan, Issac George and B. Arul

ABSTRACT

The most commonly used drugs in the Vinayaka Mission’s Kirupananda Variyar Medical College and Hospitals; Salem is β-adrenergic antagonists (β-blockers) and the α2-adrenergic agonists. So we carried out the study comparing the efficacy, cost effectiveness between timolol maleate 0.5% w/v eye drops and brimonidine tartarate 0.2% w/v eye drops in primary open angle glaucoma. It was a comparative, randomized, retrospective study. The case records of 160 glaucoma patients treated with timolol maleate and brimonidine tartarate in the ophthalmology department were collected during the period of six months. A thorough literature survey was done on the area of the project to review the past work. From this study we conclude that timolol maleate 0.5% w/v shows the greater reduction in the intra ocular pressure and is cheaper and affordable for the glaucoma patients than the brimonidine tartarate 0.2% w/v.

Keywords: Glaucoma, Intra ocular pressure, Timolol maleate, Brimonidine tartarate.