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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57



Manikya Latha S.* and V. V. V. Satyanarayana


Aim and Objective: Psoriasis is a chronic inflammatory skin disorder affecting 1-3% of the population. Psoriasis may act as an external indicator of underlying immune and metabolic dysregulation. The present study aims to know the prevalence of metabolic syndrome in Psoriatic patients and also prevalence of individual components of syndrome. Materials and Methods: 100 patients of psoriasis confirmed by histopathological examination, aged >25yrs. Age and sex matched controls were included in the study. severity of psoriasis was assessed according to Psoriasis Area and Severity Index[PASI] and body surface area[BSA]. Metabolic syndrome was diagnosed by the presence of at least 3 criteria of NCEP ATP III with Asian modification for waist circumference. The markers of metabolic syndrome in psoriatic patients and nonpsoriatic controls which includes Abdominal obesity, Blood pressure Fasting blood glucose level was measured using a glucose oxidase method. Serum triglyceride level, Serum HDL level are measured with enzymatic procedures. Results: In the present study prevalence of metabolic syndrome in psoriatic patients was higher than in controls [42.0% vs 22.0%] and association between psoriasis and metabolic syndrome was statistically significant. Prevalence of abnormal fasting blood sugars was more in psoriasis patients than controls [56.0% vs 24%]. HDL levels are low in psoriatic patients than in controls [58% vs 32%]. Serum triglycerides levels are higher in Psoriatic patients than in controls(41.0% vs 35%). Abnormal blood pressure was more in psoriatic patients than in controls [37% vs 12%]. Central obesity was more in psoriatic patients than in controls [42% vs 18%]. Conclusion: Our study showed higher prevalence of metabolic syndrome in psoriatic patients than in controls. Prevalence of components of metabolic syndrome: diabetes, hypertention, obesity and dyslipidemia was higher in psoriatic patients than controls and significant statistical association was found with Central obesity, Hypertension, Fasting glucose and low HDL levels.

Keywords: diabetes, hypertention, obesity and dyslipidemia.

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia