PERIPHERAL RETINAL NERVE FIBRE LAYER (RNFL) THICKNESS AND ITS CORRELATION WITH HIGH MYOPIA: A NOVEL EXCLUSIVE NORMOGRAM
Abdul Waris*, Adil Asghar, Mousami Malakar, Humayun Asharf, Syed Nasir Askari, Anupam Ahuja and Syed Mobashir Yunus
Purpose: To evaluate the association of high myopia with retinal nerve fibre layer (RNFL) thickness specially in the peripheral retina after ruling out other causes of RNFL thinning. METHODS: Fifty highly myopic eyes and forty emmetropic eyes of patients was selected after excluding concomitant ophthalmic disorder and RNFL thickness
measured using the Fourier domain optical coherence tomography (FD OCT). RESULTS: The overall mean RNFL thickness in the myopic groups and control were 87.89 μm and 111.64 μm respectively. The mean retinal nerve fibre thickness was significantly less in myopic eyes as compared to control group (p =0.0000). Mean loss of retinal thickness at periphery was 21.22±9.27 % and it strongly correlated with spherical error (r2=0.20). CONCLUSIONS: Retinal nerve fibre thickness was significantly decreased in myopic eyes as compared to emmetropic eyes. The peripheral retinal & RNFL of periphery are more stretched and affected in high myopia. Hence, if we focus on the RNFL of periphery after ruling out other disorder specially open angle glaucoma we get an exclusive correlation of RNFL thickness and high myopia which avoid wrong interpretation.
Keywords: RNFL (retinal nerve fibre layer), OCT (optical coherence tomography), Myopia, Normogram.
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