EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

OUTCOME AND DETERMINANTS OF OUTCOME OF STATUS EPILEPTICUS AT DISCHARGE IN INDIAN CHILDREN

Mishra Ashwani Kumar* and Srivastava Kavita

ABSTRACT

Background: Status epilepticus is a medical emergency that requires rapid and aggressive treatment to prevent systemic complications and neurological damage. Few Indian studies on outcome of pediatric SE are available. Objective: To evaluate the outcome and determinants of outcome of status epilepticus in children at discharge. Materials and methods: A cross-sectional hospital based study was undertaken of cases with status epilepticus admitted to the pediatric ward or PICU in a tertiary care center between September 2013 to March 2015. They were studied for their demographics, clinical presentation and evaluated with regards to development of epilepsy, focal motor deficit and mortality at discharge. Results: Of the 39 subjects enrolled for the study, 5 (12.8%) died. 64% subjects were less than 5 years of age and 61.5% were males. 15.4% had a family history of epilepsy. 25.6% subjects had a seizure duration of > 1 hour. 74% had symptomatic etiology, 10% had idiopathic etiology and for the rest etiology was unknown. All 21 subjects who showed delayed development on admission had poor outcomes. There was a significant positive correlation between (p=0.037) between the presence of prenatal insult either in terms of HIE, hypoglycemia or neonatal seizures and poor outcomes on discharge. Conclusion: Children who had prior developmental delay orperinatal insult had significantly worse outcomes in terms of high seizure frequency with moderate to severe cognitive or motor delay.

Keywords: Status epilepticus, outcome, determinants, discharge.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia