EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

ORGANOTOXICITY OF CADMIUM CHLORIDE ON THE FRESH WATER FISH LABEO ROHITA

*Pawlin Vasanthi Joseph and Nithya R.

ABSTRACT

Toxicity is a measure of the degree to which something is toxic or poisonous. Several toxic substances entering into aquatic organisms daily may be very small and therefore, often no apparent or sudden effects are noticeable. However, this may result into impairment of many vital functions thus gradually affecting fish population indirectly. Cadmium is a rare element and is usually found as an impurity in ores of other metals principally those of zinc. The present study aims to determine the effects of sub chronic exposure of inorganic cadmium in the inland fish Labeo rohita by observing the histopathological changes in the vital organs like gills, liver and kidney. The LC50 at 96 hrs was determined by the Probit analysis method. The experiment was designed to expose the fish to different concentrations of cadmium chloride - 500μg/l, 700μg/l, and 900μg/l. One trough served as the control. Destruction to the gills is observed in certain areas. Pronounced changes like fusion of lamellae were observed. Severe damage and marked proliferation were seen in the liver. In the kidney a reduction in the size of the epithelial cells lining the tubules was found. The study can be considered as a good bio-marker to access the health status of fishes as well as the worsening status of aquatic bodies in relation to metallic contaminants particularly cadmium.

Keywords: toxicity, cadmium, histopathology, proliferation, sub-chronic exposure, LC50 Contaminants.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia